CMOS Biochip
Mature semiconductor manufacturing can support device-to-device consistency, scalable production, and lower long-term cost.
CMOS-AI smart electroporation
Sotai Biosystems
Building a semiconductor-enabled platform to make cell transfection and cell engineering more reproducible, less damaging, and easier to scale.
CMOS
Biochip architecture for manufacturable, repeatable cell-processing devices.
AI
Parameter optimization across pulse conditions, payloads, viability, and outcomes.
Cell Engineering
Designed for DNA, mRNA, siRNA, proteins, CRISPR/Cas, and primary-cell workflows.
Platform
From bulk electroporation to controllable cell-scale processing.
Sotai combines CMOS biochips, microelectrode arrays, pulse-control electronics, and biological readouts into a reproducible transfection feedback loop.
Microelectrode Arrays
Localized electric-field control enables more precise interaction among field strength, cell state, and payload delivery.
Smart Pulse Control
Standardized pulse delivery is designed to reduce operator variation and improve repeatability across experiments.
Low-Damage Workflow
The platform balances delivery efficiency with viability, recovery, expansion potential, and downstream cell function.
AI relevance
Structured biological process data for AI-driven optimization.
Sotai is designed to connect chip behavior, pulse parameters, cell response, payload type, transfection efficiency, viability, recovery, and functional outcomes.
- Cell type and payload-aware parameter search
- Efficiency, viability, and recovery as optimization objectives
- Experiment tracking for reproducible process development
- Future acceleration with GPU-enabled modeling and analytics
Applications
One delivery bottleneck across many high-value workflows.
Modern biomedical development needs delivery tools that are efficient, gentle, measurable, and easier to transfer from research to product development.
Cell Therapy
CAR-T, immune-cell engineering, and sensitive primary-cell workflows.
Gene Editing
CRISPR/Cas delivery, knockout studies, and non-viral engineering.
mRNA Medicine
mRNA delivery, expression screening, and process development.
Biomanufacturing
Repeatable cell-processing workflows for R&D, CDMO, and translational use.
Company
Taiwan-incorporated biomedical technology startup.
Sotai Biosystems is developing a CMOS-AI smart electroporation platform at the intersection of semiconductors, biological process control, and AI optimization.
Stage
Early platform validation
Financing need
USD 2M / NT$50-60M
Seeking
Strategic partners, AI infrastructure, CMOS ecosystem access
Contact
Build AI-driven cell engineering infrastructure with Sotai.
We welcome discussion with startup programs, strategic investors, semiconductor partners, healthcare AI teams, translational research groups, and biomanufacturing collaborators.
Business / Founder Contact
Dr. Chun-Lung Lien
Sotai Biosystems
andrew0958.bt99g@g2.nctu.edu.tw
+886-905-936-000